对大容量可控喷气注射系统的最佳驱动压力进行实验研究
Dongping Zeng1, Zheng Tang1, Wei Wang1
1School of Energy and Power Engineering, Changsha University of Science and Technology, Changsha, 410114, China.
Medical engineering & physics
|August 27, 2023
概括
为大容量 (1.0毫升) 药物输送优化气动喷气注射系统,需要精确控制双相驱动压力. 1.00 MPa和0.50 MPa的理想组合确保了高效的注射性能和受控的释放.
科学领域:
- 生物医学工程 生物医学工程
- 药物输送系统 药物输送系统
- 药理动力学 药理动力学
背景情况:
- 喷射注射比传统的针式注射方法具有优势.
- 气动喷气注射系统可以为疫苗接种等应用提供更大的体积 (高达1毫升).
- 控制驾驶压力是实现所需药物输送速度和数量的关键.
研究的目的:
- 为了确定最佳的两相驱动压力组合,以实现高效的1.0毫升大容量喷气注射.
- 量化分析可控制气动喷气注射系统的动态,分散和药理学特征.
主要方法:
- 使用可控制的气动喷气注射系统.
- 研究了第一阶段1.00 MPa的驱动压力与第二阶段0.25至0.90 MPa的压力相结合.
- 分析了注射速度,分散模式和药物动力学概况.
主要成果:
- 对于1.0毫升喷射的最佳驱动压力组合被发现大约是 (1.00-0.50) MPa.
- 实现的注射速度为151.85 m/s (第一阶段) 和102.01 m/s (第二阶段),促进了最佳性能.
- 在确定压力设置的情况下,证明了 1.0 mL 喷射体积的控制释放.
结论:
- 两相 (1.00-0.50) MPa 的驱动压力策略对于大容量 (1.0 mL) 喷气注射是有效的.
- 这种优化的压力组合提高了注射效率,并确保了药物释放的控制.
- 这些发现支持大容量可控喷气注射系统的临床应用.
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