预防性使用 安福特里辛B在患有由中性衰竭复杂的血液病患者中的使用:系统性审查和元分析
Zhaoyan Chen1, Qiyi Feng2, Xiaoxing Wang3
1Department of Pharmacy, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, People's Republic of China.
Scientific reports
|August 27, 2023
概括
在患有血液学疾病和中性质衰竭的患者中,安福特乙的预防性使用显著降低了真菌感染率. 然而,它没有显示出对死亡率或殖民发生率的重大影响.
科学领域:
- 血液学 血液学 血液学
- 传染性疾病 传染性疾病
- 临床药房 临床药房
背景情况:
- 血液学疾病中的中性症增加了对侵入性真菌感染的易感性.
- 预防性抗真菌治疗对于管理这种高风险人群至关重要.
- 氨酸B是一种强大的抗真菌剂,在预防中发挥作用.
结论:
- 预防性安福特里辛B是有效的降低真菌感染率中性衰竭患者的血液疾病.
- 目前的证据不支持预防性使用显著减少死亡率或殖民.
- 由于现有研究的数量和质量的限制,进一步的高质量研究是合理的.
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