关于B7-H3用于癌症免疫治疗的全球研究趋势:参考文献分析 (2012-2022)
Xiaojuan Huang1, Jing Guo1, Shasha Wang1
1Department of Oncology, Qingdao Cancer Institute, The Affiliated Hospital of Qingdao University, Qingdao, China.
Human vaccines & immunotherapeutics
|August 28, 2023
概括
本文献分析显示,B7-H3在癌症免疫疗法 (CI) 方面的研究显著增加. 未来的趋势表明,将重点放在嵌合抗原受体和基于B7-H3的CI的向途径上.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 图书统计学 图书统计学
背景情况:
- 免疫疗法已经改变了癌症治疗.
- B7-H3 是癌症免疫疗法 (CI) 的新兴目标.
- 了解B7-H3对CI的研究趋势至关重要.
研究的目的:
- 为CI进行B7-H3的文献分析.
- 评估当前的研究环境,并确定未来的趋势.
主要方法:
- 来自Web of Science核心集合的555篇出版物的图书法分析.
- 使用VOSviewer,R包和在线平台进行数据分析.
- 包括关键词聚类和趋势分析.
主要成果:
- 自2018年以来,年度出版物显著增加,中国和美国是领先的国家.
- 苏州大学和四川大学在出版物方面领先.
- 关键的研究集群包括"免疫疗法"",协同刺激分子"",B7家族"和"PD-L1".
结论:
- B7-H3 是一个受欢迎的研究主题,对癌症免疫治疗有着重要的临床影响.
- 未来的研究很可能将重点放在嵌合式抗原受体,途径和向B7-H3.3上.
- 基于B7-H3的CI预计将推动新的研究方向.
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