一个成本效益模型,比较尿路生物标志物与尿液排尿表,用于诊断儿童泌尿盆腔结口阻塞
Geminiganesan Sangeetha1, Ramesh Babu2
1Department of Pediatric Nephrology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Journal of Indian Association of Pediatric Surgeons
|August 28, 2023
概括
尿路生物标志物显示出用于诊断尿管皮层结节阻塞 (UPJO) 的前景. 虽然目前的效果不如尿液光学 (DR) 效果,但未来的生物标志物面板可能会提供一个具有成本效益的,不那么侵入性的替代方案,减少辐射暴露.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 生物标志物发现发现
- 卫生经济学 卫生经济学
背景情况:
- 尿路皮层结节阻塞 (UPJO) 诊断依赖于诸如尿液图 (DR) 等方法.
- 尿路生物标志物正在被探索为UPJO的潜在诊断工具.
- 这些诊断方法的成本效益是关键考虑因素.
研究的目的:
- 为了比较尿路生物标志物的成本效益与用于诊断UPJO.JO的常规利尿尿表 (DR) 的成本效益.
- 评估个人和基于小组的尿路生物标志物的诊断准确性和经济影响.
主要方法:
- 使用增量成本效益比率 (ICER) 模型进行成本效益分析.
- 来自单一中心的生物标志物测定和再生图的成本数据来源.
- 从相关科学出版物中提取了DR和尿路生物标志物的精度数据.
主要成果:
- 单个尿路生物标志物目前比DR更便宜,但效果不如DR.
- 一个尿路生物标志物的小组证明了成本效益的提高,ICER可能达到负值 (成本节省).
- 生物标志物的准确性提高与更好的ICER相关;未来的成本削减预计与更高的样本量.
结论:
- 单个尿路生物标志物在UPJO诊断中尚未像DR那样有效,但成本更低.
- 生物标志物面板在UPJO诊断中具有显著的成本效益的未来潜力.
- 生物标志物面板可以减少对侵入性DR的依赖,从而最大限度地减少患者的辐射暴露.
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