在2型糖尿病患者中评估呼吸障碍感觉
Chadia Mizab1, Enric Sánchez2,3,4, Liliana Gutiérrez-Carrasquilla1
1Endocrinology and Nutrition Department, University Hospital Sant Joan de Reus, Reus, Spain.
Frontiers in endocrinology
|August 28, 2023
概括
患有2型糖尿病 (T2D) 的人体验增加了呼吸困难. 二型糖尿病患者的代谢控制和病与这种感觉有关,这凸显了更好的糖尿病管理的必要性.
科学领域:
- 肺部医学 肺部医学
- 内分泌学 在内分泌学.
背景情况:
- 2型糖尿病 (T2D) 与对肺功能障碍的敏感性增加有关.
- 评估喘息的感觉对于了解T2D相关的健康并发症至关重要.
研究的目的:
- 与对照组相比,评估2型糖尿病 (T2D) 患者呼吸困难的感觉.
- 为了确定与T2D患者呼吸困难增加相关的危险因素.
主要方法:
- 一项涉及592名参与者的横截面研究,包括353名T2D和139名对照,没有已知的呼吸系统疾病.
- 使用修改后的医学研究委员会 (mMRC) 问卷来评估呼吸困难.
- 向一小部分参与者使用圣乔治呼吸道问卷 (SGRQ).
主要成果:
- 患有T2D的患者报告的mMRC得分明显高于对照组 (p<0.001).
- 在T2D组中观察到mMRC得分≥2的更高患病率 (20.2%对11.6%,p=0.004).
- 在mMRC≥2的T2D患者中,发现了更高的HbA1c,更长的糖尿病持续时间和脏病发病率的增加. T2D本身,HbA1c和糖尿病病预测了较高的mMRC得分.
结论:
- 与没有糖尿病的人相比,患有T2D的人表现出更强烈的呼吸不良 (呼吸困难) 感觉.
- 低血糖控制 (较高的HbA1c) 和糖尿病病是T2D患者呼吸困难的重要预测因素.
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