菌类传染病:流行病学,考虑因素,治疗选择和治疗差距
Adelaide A Hebert1, Neal Bhatia2, James Q Del Rosso3
1Dr. Hebert is with UTHealth McGovern Medical School in Houston, Texas.
The Journal of clinical and aesthetic dermatology
|August 28, 2023
概括
菌传染性 (MC) 是一种常见的病毒性皮肤感染. 本次审查涵盖了MC的流行病学,治疗选择,并确定了这种广泛存在的疾病的当前管理策略中的差距.
科学领域:
- 皮肤病学 皮肤病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 虫传染病 (Molluscum contagiosum,简称MC) 是全球普遍存在的病毒性皮肤感染,影响不同年龄组,特别是儿童和免疫力低下的人.
- 肌痛性皮肤病约占所有皮肤疾病的1%,经常与亚托皮炎有关,通常呈现为具有延长解脱时间的自我限制性疾病.
- 从历史上看,缺乏确定的一线治疗方法和FDA批准的疗法导致了"良性疏忽"的方法,可能会加剧感染传播和患者的不适.
研究的目的:
- 审查目前Molluscum contagiosum的流行病学数据.
- 探索现有的MC治疗选择.
- 为了确定MC的管理中的治疗缺口.
主要方法:
- 关于MC流行和发病率的流行病学数据的文献综述.
- 对各种MC治疗方式的已发表研究进行分析.
- 评估当前的临床指导方针和治疗MC的建议.
主要成果:
- 在全球范围内,MC影响儿科,性活跃的年轻成年人和免疫受损人群,患病率越来越高.
- 虽然有几种治疗方法,但只有一个局部利丁药物设备产品是FDA批准的MC.
- "良性疏忽"的方法,源于缺乏批准的第一线治疗方法,可能导致长期感染,传播和心理社会困扰.
结论:
- 对于Molluscum contagiosum的更成熟和更容易获得的第一线治疗选择有很大的需求.
- 解决MC管理中的治疗缺口对于减少感染持续时间,身体不适和心理社会影响至关重要.
- 进一步研究和开发有效的MC疗法是有必要的,以改善患者的治疗结果.
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