在儿科肺炎中早产和检测常见的呼吸道病原体
Xin-Rui Wang1,2, Juan Du1,2, Shan-Shan Zhang1,2
1Department of Laboratorial Science and Technology & Vaccine Research Center, School of Public Health, Peking University, Beijing 100191, P.R. China.
iScience
|August 28, 2023
概括
早产婴儿的肺炎与更严重的结果和特定的细菌感染有关,如大肠杆菌. 与晚期早产相比,早产造成严重肺炎的风险更高.
科学领域:
- 儿科 儿科 儿科
- 新生儿科学 新生儿科学
- 传染性疾病 传染性疾病
背景情况:
- 婴儿期肺炎可能导致长期健康问题.
- 过早分娩是各种新生儿并发症的已知危险因素.
研究的目的:
- 为了研究早产婴儿肺炎的临床后果.
- 为了比较早产和早产儿之间的病原体检测率和肺炎的严重程度.
- 为了确定与早产和晚产相关的特定风险.
主要方法:
- 在2009年至2021年期间,对8206名被诊断患有肺炎的儿童进行了回顾性分析.
- 检测和比较20种呼吸道病原体.
- 早产婴儿的分层分为早产 (246) 和晚产 (533) 组.
主要成果:
- 病毒病原体检测率在早产和长期组之间是相似的.
- 在早产婴儿中,对大肠杆菌和肺炎的阳性率较高.
- 在早产婴儿中,严重的肺炎发生的频率更高 (总体为16.52%),在早产婴儿子组中,发病率最高.
结论:
- 早产影响了儿童肺炎中的细菌病原体检测.
- 过早分娩是发展严重肺炎的独立风险因素.
- 早期早产与与晚期早产相比,严重肺炎的风险明显更高.
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