在基本高血压中对急性精神压力的生理反应性-系统性审查
Lisa-Marie Walther1,2, Petra H Wirtz1,2
1Biological Work and Health Psychology, University of Konstanz, Konstanz, Germany.
Frontiers in cardiovascular medicine
|August 28, 2023
概括
基本高血压与对急性精神压力 (AMS) 的过度生理反应有关,尤其是强烈的压力. 本综述综合了多个生理系统的研究结果,证实了高血压患者的高反应性.
科学领域:
- 心血管生理学心血管生理学
- 高血压研究 高血压研究
- 应激反应系统 应激反应系统
背景情况:
- 对急性精神压力 (AMS) 的过度生理反应与高血压的发展和心血管疾病 (CVD) 风险有关.
- 现有的研究比较了基本高血压 (HT) 和正常血压 (NT) 个体的AMS反应性.
- 缺乏对应力反应系统和中等心血管疾病风险因素进行全面的系统审查.
研究的目的:
- 系统地审查和综合有关在基本高血压中对AMS的生理反应性的发现.
- 为了比较HT和NT个体之间的各种应激反应生理系统的AMS反应性.
- 确定在高血压中普遍生理过敏反应的潜在模式和机制.
主要方法:
- 在PubMed的系统文献搜索中寻找原创文章和简短报告 (2022年11月至12月).
- 包括比较HT和NT个体对认知,公开演讲或联合AMS的反应性的研究.
- 专注于评估至少一个预定义的应激反应生理系统的研究.
主要成果:
- 总共有58个出版物被纳入了审查.
- 与NT相比,HT个体在所有研究系统中对强AMS的生理反应性增加.
- 在HT中对轻度/中度AMS的反应性取决于条件,在特定情况下或压力特征下观察到.
结论:
- 这一系统性审查支持基本高血压中对AMS的普遍生理过敏反应,特别是对强烈的压力因素.
- 这些发现强调了压力强度在调节HT的生理反应中的重要性.
- 对潜在机制的进一步研究对于全面了解高血压中AMS高反应性至关重要.
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