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病例报告:对转移性肺癌患者的ALK-TKI反应,具有形态异质性和一致的分子特征

Yu Yang¹, Han Liu¹, Tao-Hua Liu¹

¹Department of Pathology, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China.

Frontiers in oncology

|August 28, 2023

概括

这种罕见的肺腺癌病例突出了由于异质组织学的诊断挑战. 尽管有共同的ALK突变,但在原发性与转移性部位对ALK-TKI治疗的不同反应提供了关键的见解.

科学领域:

在瘤学瘤学.
遗传学遗传学是一个
病理学病理学病理学

背景情况:

肺腺状细胞癌 (ASC) 是一种罕见的癌症,具有混合腺状细胞癌 (ADC) 和状细胞癌 (SQCC) 组成部分.
有限的活检采样可能导致纯组织学错误诊断,使治疗决策复杂化.
身体突变和基因重组对于识别可操作的标和理解瘤克隆进化至关重要.

关键词:

ALK 的重新安排.状腺癌 (Adenosquamous Carcinoma) 是一种状腺癌.组织形态学组织形态学转移的肺癌转移的肺癌有针对性的治疗.

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