克莱布西拉肺炎 (Klebsiella pneumoniae) 操纵人类巨细胞以获得铁

Philipp Grubwieser1, Richard Hilbe1, Clemens Michael Gehrer1

  • 1Department of Internal Medicine II, Infectious Diseases, Immunology, Rheumatology, Pulmonology, Medical University of Innsbruck, Innsbruck, Austria.

PubMed
概括

克莱布西拉肺炎可以操纵巨细胞的铁,使其在宿主细胞内存活. 这涉及通过STAT-6-IL-10通路诱导转激素受体1 (TFR1),可以针对新的抗菌疗法.