在马里,患者的性别和肺外结核病的解剖部位之间的关系
Bocar Baya1,2, Ibrahim Sanogo1, Mahamadou Kone1
1University Clinical Research Center (UCRC), Faculty of Pharmacy and Faculty of Medicine and Odonto-Stomatology, University of Sciences, Techniques, and Technologies of Bamako (USTTB), Mali, West Africa.
患者的性别会影响肺外结核 (EPTB) 的发生地. 男性更容易患上肺部EPTB,而女性患淋巴结和腹部EPTB的比例更高.
科学领域:
- 医学研究 医学研究
- 传染病 传染病 传染病
- 公共卫生 公共卫生
背景情况:
- 影响对肺外结核病 (EPTB) 易感性的宿主因素尚不清楚.
- 调查患者的性别作为EPTB局部化的决定因素对于了解疾病动态至关重要.
研究的目的:
- 研究患者性别对肺外结核病的解剖分布的影响.
- 为了确定EPTB本地化中的基于性别的差异.
主要方法:
- 在西非马里进行的回顾性横截面研究.
- 从1,304个疑似EPTB病例 (2019-2021) 的医院记录分析.
- 专注于确认的EPTB病例 (n=1,012),以评估性别特定的解剖部位流行率.
主要成果:
- 在确诊的EPTB病例中观察到男性占主导地位 (1.59:1比).
- 排骨结核病在男性中明显更常见 (OR: 1.51).
- 淋巴结和腹结核在男性的几率较低,而女性的几率较低 (分别为0.57和0.59).
结论:
- 在受肺外结核病影响的解剖部位存在显著的基于性别的差异.
- 腹腔EPTB与男性有关,而淋巴结和腹腔EPTB在女性中更为普遍.
- 需要进一步的研究来阐明性别在EPTB地点偏好的作用.
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