在一个9岁的患有B细胞急性淋巴细胞白血病的孩子身上,阿斯伯吉洛症和肺结核的同时感染
Wirapatra Iamwat1, Krit Cheawcharnprapan2, Patcha Yenjabog3
1Division of Pediatric Pulmonary and Critical Care, Department of Pediatrics, Faculty of Medicine, Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
Oxford medical case reports
|August 28, 2023
概括
这份病例报告详细介绍了一名儿科白血病患者的侵袭性阿斯伯吉洛症和Mycobacterium结核病 (MTB) 罕见的同时感染. 管理这种双重感染需要仔细考虑药物相互作用,以获得有效的治疗.
科学领域:
- 儿童传染病 儿童传染病
- 血液学-瘤学 血液学-瘤学
- 菌类学和菌菌学.
背景情况:
- 侵袭性阿斯伯吉洛症和Mycobacterium结核病 (MTB) 的同时感染在儿科患者中很少见.
- 这起案件涉及一名9岁的泰国女孩,患有B细胞急性淋巴细胞白血病,正在接受化疗.
研究的目的:
- 报告B细胞急性淋巴细胞白血病的儿科患者罕见的侵袭性阿斯伯吉洛症和MTB共感染病例.
- 突出这一双重感染的诊断挑战和管理策略.
- 强调在联合治疗方案中考虑药物相互作用的重要性.
主要方法:
- 一个9岁的泰国女孩患有B细胞急性淋巴细胞白血病的案例介绍.
- 诊断工作包括胸部计算机断层扫描 (CT),大脑CT血管造影和切除.
- 鉴定了真菌元素 (septate hyphae) 和酸性细菌 (AFB) 证实了共感染.
主要成果:
- 患者在化疗期间出现了长期发烧性中性质.
- 图像检测显示了带有空气新月标志的肺结节和感染的破裂脑动脉瘤.
- 组织病理学和PCR证实了侵入性阿斯伯吉洛症和Mycobacterium结核病.
结论:
- 侵入性阿斯伯吉洛斯和MTB共感染在儿科瘤患者中提出了重大挑战.
- 及时准确的诊断对于启动适当的抗真菌和抗结核联合治疗至关重要.
- 仔细考虑药物相互作用对于有效的管理和改善患者结果至关重要.
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