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Updated: Jul 18, 2025

Assays for Validating Histone Acetyltransferase Inhibitors
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库库醇具有不寻常的激素脱乙酶增强活性,可以抵制转移性瘤中的免疫逃逸

Samantha L S Ellis1,2,3,4, Sarah Dada1,2,3,4,5,6, Lilian L Nohara1,2,3

  • 1Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada.

Frontiers in pharmacology
|August 28, 2023
PubMed
概括

库库醇是一种天然化合物,可以通过增强抗原呈现机制 (APM) 来恢复癌细胞的免疫识别. 这种饮食成分修改了表观遗传程序,可能引导免疫力对抗侵袭性癌症.

关键词:
在HDAC的基础上,HDAC是抗原加工机械的使用.这是一种曲醇 (curcuphenol).发现药物的发现.表观遗传修饰是一种表观遗传修饰.基因组脱乙酶的活性主要的组织相容性复合物I类.瘤是一种瘤.

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