在患有抗脂综合征和抗质底膜抗体的患者中补充介导的血栓性微血管病变
Tara L Gallant1, Emily Zheng1, Alicia M Hobbs2
1College of Medicine, California Northstate University College of Medicine, Elk Grove, USA.
Cureus
|August 28, 2023
概括
补充介导的血栓性微血管病变 (TMA) 可以模仿抗质底膜疾病. 及时诊断和以eculizumab等向疗法治疗对于患者的康复至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 血液学 血液学 血液学
- 免疫学 免疫学 免疫学
背景情况:
- 血栓性微血管病变 (TMA) 包含有血栓细胞减小,血液溶解性贫血和器官损伤的情况.
- 补充介导的TMA是由于失调的替代补充通路激活引起的,通常是由于调节性蛋白质缺乏.
- 抗质底膜 (anti-GBM) 疾病是一种严重的血管炎,由针对IV型原蛋白的自身抗体引起.
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