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COVID-19中的纤维细胞生长因子23:一个观察性研究

Athena Myrou¹, Theodoros Aslanidis², Keli Makedou³

¹Department of Internal Medicine, American Hellenic Educational Progressive Association (AHEPA) University Hospital, Thessaloniki, GRC.

|August 28, 2023

概括

在COVID-19患者中,纤维细胞生长因子23 (FGF23) 水平显示出变化,但与常见的实验室标记物没有发现显著的相关性. 需要进一步的研究来确定FGF23和COVID-19严重程度之间的可靠联系.

科学领域:

内分泌学在内分泌学.
传染性疾病传染性疾病
生物标志物研究生物标志物研究

背景情况:

纤维细胞生长因子23 (FGF23) 是内分泌FGF家族的一部分.
FGF23被认为是一种潜在的生物标志物和治疗标.
关于FGF23和COVID-19之间的相互作用的数据有限.

研究的目的:

为了调查COVID-19患者的FGF23水平.
为了将FGF23水平与炎症标志物和其他实验室参数相关联.

主要方法:

涉及81名COVID-19患者的前性观察性研究.
对血清FGF23水平的分析.
与生物化学,全血细胞计和凝血参数的相关性.

主要成果:

血清FGF23水平在不同性别和年龄组中是相似的.
在整体队列中,没有观察到FGF23和生物化学,血清或凝血参数之间的显著相关性.
在不同年龄组中观察到FGF23水平的变化.

结论:

在症状性COVID-19感染中,FGF23水平可能会波动.
需要更大,更精心设计的研究来确认FGF23和COVID-19中的实验室参数之间的可靠相关性.

关键词:

临床生物标志物临床生物标志物在COVID-19感染病例中,fgf2323 在线观看纤维细胞生长因子 23 23 感染感染的感染.

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