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Updated: Jul 18, 2025

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结合β-hairpin序列动图来增加基于的PROTAC的细胞内稳定性

Hannah C Hymel1, Jeffery C Anderson1, Dong Liu2

  • 1Cain Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA, 70803.

Biochemical engineering journal
|August 28, 2023
PubMed
概括

这项研究表明,β-hairpin序列可以作为细胞透和降解蛋白质溶解向嵌合体 (PROTACs) 的降解子,改善向降解和细胞寿命.

关键词:
这就是PROTAC.基于的治疗药物.这就是β-hairpin.

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