从轻度COVID-19中康复的患者的选择性手术的资格:一种倾向匹配分析
Fuzhen Zhang1, Lichao Di1, Sufang Jiang1
1Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China.
Journal of surgical oncology
|August 28, 2023
概括
从轻度COVID-19 (冠状病毒疾病2019) 恢复过来的患者可以在康复后至少7天接受选择性手术. 这种时间避免了手术后并发症或在30天内死亡的风险增加.
科学领域:
- 医学研究 医学研究
- 外科手术的结果
- 传染病流行病学 传染病流行病学
背景情况:
- SARS-CoV-2的Omicron变种 (严重急性呼吸系统综合征冠状病毒2) 导致了广泛的感染.
- 了解COVID-19感染后选择性手术的最佳时间对于患者安全和医疗保健政策至关重要.
- 之前关于COVID-19后手术时间的指导方针有所变化,需要与最近的变种相关的具体数据.
研究的目的:
- 调查在Omicron变种感染后选择性手术时间和术后结果之间的关联.
- 为临床医生,政策制定者和患者提供基于证据的建议,以确定COVID-19后恢复后手术时间.
主要方法:
- 根据EQUATOR-STROBE指南进行了单中心,倾向匹配的分析.
- 根据从症状缓解到手术的间隔,患者被分为三组:≤7天,8-14天和>14天.
- 评估的结果包括术后呼吸道并发症,血管血栓,心肌梗塞,缺血性中风和30天死亡率.
主要成果:
- 在倾向匹配后,对227名从COVID-19中恢复过来的患者和2043名SARS-CoV-2阴性患者的队列进行了比较.
- 与SARS-CoV-2阴性组相比,手术后呼吸道并发症的发生率在经历手术 ≤7天后的组中明显高 (15.91%对6.71%).
- 在其他30天结局 (血管血栓,心肌梗塞,缺血性中风,死亡率) 中,在COVID-19康复组和对照组之间没有观察到统计学上显著的差异.
结论:
- 从轻度COVID-19感染中恢复后至少7天,选择性手术似乎是安全的.
- 当手术在症状消失7天或更长时间后进行时,患者不会出现30天术后并发症或死亡的风险增加.
- 这些发现支持更新的临床指导方针,用于在有轻度COVID-19病史的患者手术时间.
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