男性乳腺癌的预后因素:一个单心经验
Wala Ben Kridis1, Mayssa Lajnef1, Faida Bouattour1
1Department of Medical Oncology, Habib Bourguiba Hospital, University of Sfax, Sfax, Tunisia.
Breast disease
|August 28, 2023
概括
男性乳腺癌 (MBC) 是罕见的,但这项研究发现突尼斯男性的预后不佳的因素,如晚期和淋巴结参与. 所有的MBC病例都显示出阳性激素受体,与女性乳腺癌不同.
科学领域:
- 在瘤学瘤学.
- 医学研究 医学研究
背景情况:
- 男性乳腺癌 (MBC) 是一种罕见的恶性瘤,仅占所有乳腺癌病例的1%.
- 了解MBC的预后因素对于改善患者结果至关重要.
研究的目的:
- 分析男性乳腺癌 (MBC) 的临床和病理预后因素.
主要方法:
- 在2005年至2020年期间,对32名被诊断和治疗为原发性乳腺癌的男性进行了一项回顾性研究.
- 收集的数据包括患者人口统计,瘤特征和治疗结果.
主要成果:
- MBC的发病率为1.3%,患者的中位数年龄为55岁.
- 常见的发现包括大瘤大小 (平均3.9厘米),淋巴结参与 (56.2%) 和II级瘤 (71.8%).
- 所有病例都表达了激素受体;HER2过度表达低 (6.2%),没有观察到三阴性MBC. 确定的预后因素是T4阶段,参与节点,SBR III和HER2+++.
结论:
- 突尼斯的MBC病例始终显示出积极的激素受体,与女性乳腺癌趋势不同.
- 尽管HER2的过度表达很低,并没有三阴性病例,但由于晚期,淋巴结参与,SBR III和远程转移,预后不佳.
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