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在自然和实验感染Babesia rossi的狗中产生再生反应

Chandini Seejarim¹, Yolandi Rautenbach¹, Emma H Hooijberg¹

¹Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Pretoria, South Africa.

Veterinary clinical pathology

|August 28, 2023

概括

感染Babesia rossi的狗表现出不良的再生反应,尽管严重贫血,但网状细胞数量不足表明了这一点. 这表明寄生虫可能会抑制骨髓活动.

科学领域:

兽医医学兽医医学兽医医学
血液学血液学血液学
传染性疾病传染性疾病

背景情况:

狗狗的红宝贝菌感染会导致严重的溶血性贫血.
对这种感染的再生反应通常是轻微的.

研究的目的:

在B. rossi感染的狗中比较绝对网状细胞计数 (ARC) 和指数与免疫媒介血液溶解性贫血 (IMHA) 和健康对照.
评估实验感染狗的再生反应.

主要方法:

追溯观察性研究.
来自ADVIA 2120血液学分析仪的记录分析.
包括自然感染的B. rossi狗,IMHA狗,对照狗和实验感染的狗.

主要成果:

感染B. rossi和IMHA的狗血红素比对照人数显著降低.
与对照组相比,B. rossi和IMHA组的ARC较高.
在B. rossi犬群中,ARC显著低于IMHA犬群.
经过实验感染的狗表现出ARC寄生病后检测的短暂下降,随后在治疗后增加.
自然感染的狗的网状细胞更大,尺寸更可变.

结论:

患有B. rossi的狗的再生反应对于观察到的贫血严重程度是不充分的.
这种不足可能源于直接的寄生虫抑制或宿主介导的骨髓抑制.

关键词:

绝对的网红细胞计数数.贫血贫血是一种疾病.这种疾病叫做babesiosis.狗类犬类动物狗类犬类

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