保护因素和糖尿病并发症的发病因子
Marc Gregory Yu1,2, Daniel Gordin1,2,3,4, Jialin Fu1,2
1Research Division, Joslin Diabetes Center, Boston, MA 02215, USA.
Endocrine reviews
|August 28, 2023
概括
糖尿病并发症是由代谢途径障碍引起的. 本次审查提出了新的分类,并强调了保护因素在疾病进展中与风险因素并肩发挥的关键作用.
科学领域:
- 内分泌学和新陈代谢学
- 糖尿病的病理生理学
背景情况:
- 慢性糖尿病并发症对发病率和死亡率有很大影响.
- 目前的分类将并发症分为微血管和宏血管起源.
- 正在发生一种范式的转变,重点关注糖尿病病原发生的风险和保护因素之间的相互作用.
结论:
- 需要修订糖尿病并发症的分类.
- 了解保护因素对于管理糖尿病并发症至关重要.
- 需要进一步的研究来阐明保护因素的作用和机制.
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