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Formation of Dispersible Taohong Siwu Tablets
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基于质量设计的开发里瓦罗克萨班装载的液态固体紧片,具有改进的生物制药特性

Pranav Shah1, Heta Desai2, Bhavin Vyas2

  • 1Maliba Pharmacy College, Bardoli, Gujarat, India. pranav.shah@utu.ac.in.

AAPS PharmSciTech
|August 28, 2023
PubMed
概括

液态固体紧技术改善了里瓦洛克萨班 (RXN) 的溶解性和口服生物利用性. 优化的里瓦罗克萨班液体固体紧剂 (RXN LSCs) 在老鼠中显示出增强的溶解和药物动力学特征.

关键词:
32 因素设计设计.生物可用性 生物可用性液态固体紧型 液态固体紧型抑制P-gp的抑制作用里瓦罗克萨班 (Rivaroxaban) 是一种药物.可溶性 可溶性 溶性

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