免疫复合性脑膜炎后的分散视网膜功能障碍,先前患有细胞巨血病毒视网膜炎的患者:一种新的观察
Yew Sen Yuen1, Graham E Holder2,3, Gopal Lingam4
1Department of Ophthalmology, National University Hospital, 5 Lower Kent Ridge Rd, Singapore, 119074, Singapore. yew_sen_yuen@nuhs.edu.sg.
Documenta ophthalmologica. Advances in ophthalmology
|August 28, 2023
概括
即使在成功治疗细胞巨乳病毒视网膜炎 (CMVR) 和随后的免疫复合性脑膜炎 (IRU) 后,患者也可能出现持续的视网膜功能障碍. 早期和积极的炎症控制对于保持视力至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
背景情况:
- 细胞巨乳病毒视网膜炎 (CMVR) 是免疫功能低下个体视力损失的重要原因.
- 在CMVR治疗后,随着免疫功能恢复,免疫复合性脑膜炎 (IRU) 可能发生.
- 在IRU解决后持续的视网膜功能障碍在这些患者的管理中构成了挑战.
研究的目的:
- 调查和报告免疫复合性脑膜炎 (IRU) 后的扩散性视网膜功能障碍的长期后果,这些患者先前接受过细胞巨乳病毒视网膜炎 (CMVR) 治疗.
主要方法:
- 采用了一个追溯案例系列设计.
- 分析了两个有CMVR病史和随后IRU病史的患者.
- 序列 fundus 摄影,斑点光学连贯性断层扫描和电生理学被用于评估.
主要成果:
- 这两位患者都成功地用抗病毒药物治疗CMVR,用类固醇治疗IRU.
- 尽管有解决方案,但观察到慢性视网膜损伤,包括圆形线损失和光盘缩.
- 电生理学证实了广义视网膜功能障碍,强调了有效的炎症管理的必要性.
结论:
- 在CMVR之后的IRU患者可能会表现出持续的视网膜功能障碍,即使视力敏度正常.
- 建议对炎症进行积极控制,以减轻长期视网膜损伤.
- 客观的电生理学发现强调了监测和干预的重要性.
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