在帕金森病中进行多模体脑体评估:fNIRS中的系统性审查
IEEE journal of biomedical and health informatics
|August 28, 2023
概括
像fNIRS和运动传感器这样的客观工具对帕金森病 (PD) 评估有希望. 然而,在PD患者中,大脑活动和身体运动之间的联系仍未得到充分探索,这阻碍了客观诊断.
科学领域:
- 神经科学是一个神经科学.
- 生物医学工程 生物医学工程
- 临床神经学 临床神经学
背景情况:
- 帕金森病 (PD) 会导致运动和认知障碍.
- 目前的PD管理依赖于主观的临床评估.
- 客观的诊断和严重性评估工具的研究越来越多.
研究的目的:
- 探索PD患者的大脑活动和身体运动之间的关系.
- 评估使用联合大脑和运动测量方法用于PD诊断和严重程度评估的可行性.
主要方法:
- 从Scopus数据库中对24项研究进行系统文献综述.
- 包括使用功能近红外光谱 (fNIRS) 检测大脑活动和运动评估传感器的研究.
- 专注于涉及帕金森病患者的研究.
主要成果:
- 前额叶皮质是最常被研究的大脑区域.
- 氧化血红蛋白 (HbO2) 是fNIRS的主要指标.
- 惯性测量单元 (IMU) 和电子步道是常见的运动评估工具.
- 结合大脑活动和身体运动分析是一个研究不足的领域.
结论:
- 像fNIRS和运动传感器这样的客观措施为PD评估提供了潜力.
- 需要进一步的研究来探索大脑活动和身体运动之间的关系,以改善PD诊断和管理.
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