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不相容的血输血与平民创伤患者的死亡率增加无关
Jack K Donohue1, Jason L Sperry1,2, Philip C Spinella2,3
1Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Hematology (Amsterdam, Netherlands)
|August 28, 2023
概括
在创伤患者中,不相容的血并没有增加死亡率. 这项研究发现,在接受不兼容血和兼容血的创伤患者中,24小时或30天死亡率没有显著差异.
科学领域:
- 紧急医疗 紧急医疗
- 输血医学 输血医学
- 创伤外科 手术 创伤外科
背景情况:
- 在创伤护理中使用低位数O组全血 (LTOWB) 和A组血存在ABO不兼容血输血的风险.
- 与ABO不相容的血输血可能会增加未知血型的创伤患者的发病率和死亡率.
研究的目的:
- 为了评估接受了ABO不兼容血的平民创伤患者的结果.
- 确定不兼容的血输血是否与创伤患者的死亡率增加有关.
主要方法:
- 对来自单一创伤中心的347名创伤患者进行了回顾性分析.
- 患者被分为两组:仅接受兼容血的患者和接受任何不兼容血的患者.
- 多变量分析,包括Cox比例危险回归,评估了不兼容血和24小时或30天死亡率之间的关联.
主要成果:
- 180名患者接受了不兼容的血 (中位体积:684毫升),167人仅接受了兼容的血.
- 两组之间24小时或30天死亡率没有显著差异.
- 在Cox回归模型中,不相容的血接收并不是死亡率的独立预测因素.
结论:
- 在这一创伤患者队列中,接受ABO不兼容血与死亡率的增加并没有独立相关.
- 需要进一步的前性研究来验证这些关于创伤中不兼容的血输血的发现.
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