来自可生物降解和常规塑料的二次纳米塑料对Streptomyces coelicolor M145的毒性影响的比较研究
Xiaomei Liu1, Shakeel Ahmad2, Jingkang Ma2
1College of Life Sciences, Qufu Normal University, Qufu, Shandong 273165, China; MOE Key Laboratory of Pollution Processes and Environmental Criteria/Tianjin Engineering Center of Environmental Diagnosis and Contamination Remediation, College of Environmental Science and Engineering, Nankai University, Tianjin 300350, China.
Journal of hazardous materials
|August 28, 2023
概括
像PLA和PHA这样的可生物降解塑料比传统塑料释放更多的纳米塑料,对土壤细菌构成短期毒性风险. 然而,这些纳米塑料也令人惊地促进了Streptomyces coelicolor的抗生素生产.
科学领域:
- 环境科学 环境科学
- 微生物学 微生物学
- 材料科学 材料科学 材料科学
背景情况:
- 塑料被广泛使用,但造成环境问题.
- 生物降解塑料是替代品,但可能会带来风险.
- 来自塑料的微/纳米塑料是一个新兴的环境问题.
研究的目的:
- 研究可生物降解和传统塑料中纳米塑料的短期毒性.
- 评估这些纳米塑料对Streptomyces coelicolor M145.5的影响.
- 了解对细菌生存和抗生素生产的影响.
主要方法:
- 微塑料 (PLA,PHA,PS) 的降解30天.
- 对Streptomyces coelicolor M145暴露于释放的纳米塑料.
- 细菌生存率和抗生素产量的分析 (ACT,RED).
主要成果:
- PLA和PHA释放的纳米塑料比PS更多.
- PLA和PHA纳米塑料对M145.5具有显著的毒性.
- PS纳米塑料没有显著的毒性.
- 抗生素生产 (ACT,RED) 显著增加,特别是在PLA纳米塑料处理后.
- 与抗生素生产相关的调节基因的表达增加.
结论:
- 可生物降解塑料产生的纳米塑料比传统塑料更多.
- PLA和PHA纳米塑料对S. coelicolor存在短期毒性风险.
- 纳米塑料,特别是来自PLA的纳米塑料,可以刺激S. coelicolor.中的抗生素生产.
- 需要进一步研究可生物降解纳米塑料对生态的影响.
相关概念视频
Microbial Bioremediation of Plastics
Polyethylene terephthalate (PET) is a synthetic polymer widely utilized in the packaging industry, particularly for bottles and containers. Due to its chemical stability and durability, PET accumulates in the environment, contributing significantly to plastic pollution. It comprises repeating units of terephthalic acid and ethylene glycol, resulting in a semi-crystalline structure that is resistant to natural degradation processes.A notable breakthrough in plastic biodegradation came with the...
Clinical Significance of Antibiotic Resistance
Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...


