膀癌的性别和囊切除术:一个大批量的三级泌尿器科护理中心的经验
A Mariotti1, P Spatafora1, F Sessa1
1Department of Urology, Careggi Hospital, University of Florence, Florence, Italy.
概括
性别不会显著影响膀癌存活率或激进囊切除术后的手术选择. 这项研究发现,无论治疗方法如何,男性和女性患者的瘤结局都相似.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 手术瘤学手术瘤学
背景情况:
- 在膀癌 (BC) 结果中经常报告基于性别的差异.
- 调查这些差异对于公平的患者护理至关重要.
研究的目的:
- 分析经过激进囊切除术 (RC) 的膀癌患者的性别特异性结果.
- 评估两性之间手术选择和临床结果的潜在差异.
主要方法:
- 在2016-2020年期间接受治疗的447名膀癌患者 (85名女性,362名男性) 的回顾性分析.
- 评估性别对疾病阶段,整体存活率 (OS) 和外科手术方法的影响.
- 根据瘤阶段和治疗方式进行调整的统计分析.
主要成果:
- 性别之间在手术提供,并发症,病理阶段或OS方面没有统计学上显著的差异.
- 总生存率为52.6%,癌症特异性生存率为67.6%,随访时间中位数为28.3个月.
- 机器人辅助手术和开放的正统神经膀与更高的OS率有关.
结论:
- 性别似乎不会影响激进囊切除术后的瘤结果,当调整到阶段和治疗时.
- 需要进一步的研究来探索RC后女性患者的功能结果.
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