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管理在病:旧故事,新的技巧
Rengin Elsurer Afsar1, Baris Afsar1, Talat Alp Ikizler2
1Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN; Department of Nephrology, Suleyman Demirel University Faculty of Medicine, Isparta, Turkey.
Seminars in nephrology
|August 28, 2023
概括
高摄入量增加了慢性病 (CKD) 的高血压风险. 在CKD中低饮食的证据有限,在CKD不同阶段没有明确的摄入量目标.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 心脏病学 心脏病学
- 营养科学 营养科学
背景情况:
- 过度饮食摄入与高血压有关,特别是在慢性病 (CKD) 患者中.
- 目前对CKD低饮食的建议主要是基于意见,缺乏可靠的受控研究数据.
- 摄入量与慢性病中心血管事件/死亡率之间的关系尚未得到充分证实.
研究的目的:
- 审查关于CKD中限制的挑战和证据.
- 讨论对CKD患者的摄入目标水平和评估方法.
- 检查限制干预措施及其对临床结果的影响.
主要方法:
- 关于CKD中饮食摄入量研究的文献综述.
- 流行病学数据分析,将摄入量与CKD进展,心血管风险和死亡率联系起来.
- 讨论目前的指导方针和管理CKD中摄入量的挑战.
主要成果:
- 在CKD中支持低饮食的数据主要基于意见.
- 流行病学研究表明,摄入量与CKD的不良结果之间存在不一致的关联.
- 高摄入的影响在晚期CKD中更为明显,但缺乏明确的目标水平.
结论:
- 需要更多的受控研究来确定限制在CKD中的有效性.
- 根据CKD阶段 (GFR,白尿/蛋白尿) 确定最佳的摄入目标至关重要.
- 需要有效的限制干预措施来改善CKD患者的临床结果.
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