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Updated: Jul 17, 2025

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试图通过实验工作与生物医学应用的FEM模型相结合来确定抗菌Tridax procumbens (TP) 机械性能

C Balaji Ayyanar¹, Sofiene Helaili², Sanjay Mavinkere Rangappa³

¹Department of Mechanical Engineering, Coimbatore Institute of Technology, Coimbatore, Tamilnadu, India.

Journal of the mechanical behavior of biomedical materials

|August 28, 2023

概括

本研究描述了用于伤口愈合应用的Tridax procumbens (TP) 和carboxymethylcellulose (CMC) 生物膜的机械性能. 这些发现支持TP/CMC生物膜作为有效的伤口包裹,突出了它们在医疗膜应用中的潜力.

科学领域:

生物材料科学生物材料科学
材料工程材料工程材料工程
药理学药理学是指药理学的学科.

背景情况:

药用植物,包括Tridax procumbens (TP),由于它们的抗菌特性,在伤口愈合方面至关重要.
TP证明了对黄金葡萄球菌的有效性,并有助于治疗皮肤感染.
的机械性质,特别是在固体形式或与碳素甲基纤维素 (CMC) 混合时,仍然在很大程度上没有特征.

研究的目的:

开发和表征特立达克斯 (TP) 和甲基纤维素 (CMC) 复合生物膜.
通过实验和数值建模技术来确定这些TP/CMC生物膜的机械性能.
评估TP/CMC生物膜作为生物医学应用中的伤口带的潜力.

主要方法:

通过溶液造方法将TP液体提取物与CMC混合,以创建生物膜.
拉伸强度测试使用通用拉伸测试仪 (UTT) 进行.
实验结果与在ANSYS解决器上开发的有限元数值模型 (FEM) 进行了验证.

主要成果:

纯CMC的最大拉伸应力为15.31MPa,弹性模量为7.24GPa,密度为1.62g/cm3,波松比为0.22.
50%的CMC/TP生物膜的最大拉伸应力为26.2MPa,弹性模量为2.092GPa,密度为1.276g/cm3.
FEM分析确定了纯TP的特性:弹性模量为0.225 GPa,密度为0.93 g/cm3,Poisson比为0.4,与实验数据密切匹配.

结论:

通过实验测试和FEM成功确定TP/CMC生物膜的机械性能.
TP/CMC生物膜表现出有前途的机械特性,可作为伤口包裹使用.
这项研究有助于提升TP的价值,用于先进的医疗固化膜应用.

关键词:

抗菌剂抗菌剂抗菌剂在PVA中使用PVA.在 TP TP 里面.拉力强度拉力强度拉力强度伤口愈合伤口愈合

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