皮表皮肤生物物理特性与肥胖及其影响的关联
Tingting Zhu1, Shuyun Yang2, Theodora M Mauro3
1Department of Dermatology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Skin pharmacology and physiology
|August 28, 2023
概括
肥胖与皮肤屏障功能受损有关,导致更高的水分损失和更低的水分补充. 这些表皮变化可能会使肥胖患者的炎症和皮肤状况恶化.
科学领域:
- 皮肤病学 皮肤病学
- 代谢障碍 代谢障碍 代谢障碍
- 表皮生理学表皮生理学
背景情况:
- 肥胖,体质指数 (BMI) 定义为30或更高,与许多健康问题有关,包括心血管疾病,糖尿病和脂质失调.
- 肥胖也与各种皮肤疾病有关,如亚托皮炎,牛皮,黑色黑色和皮肤感染.
研究的目的:
- 审查肥胖和表皮功能之间的关联.
- 讨论这些协会潜在的潜在机制.
- 探索对肥胖和皮肤屏障功能受损的个体的影响.
主要方法:
- 这项研究是对现有文献的综述.
- 它合成了有关肥胖个体表皮功能的证据.
- 它检查了BMI和皮肤参数之间的相关性.
主要成果:
- 肥胖个体通常表现出更高的皮层间流失水率和较低的角层水分.
- 皮肤表面pH值的结果有争议,但一项研究显示,男性的BMI和皮肤表面pH值之间存在正相关性,这表明性别特异的变化.
- 有证据表明,肥胖和表皮功能障碍之间存在联系,表皮透性屏障受损的特征.
结论:
- 肥胖与表皮屏障功能受损和皮肤水分水平较低有关.
- 皮肤表皮功能受损可能导致炎症,这也与肥胖有关.
- 改善表皮功能可能为患有肥胖的人提供治疗益处,特别是那些有现有的皮肤屏障异常的人.
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