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任务fMRI研究研究强迫症和饮食障碍患者的抑制控制:一个比较的元分析

Zheqin Li¹, Geya Tong¹, Yang Wang¹

¹Shanghai Mental Health Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry

|August 28, 2023

概括

强迫症 (OCD) 和饮食障碍 (EDs) 都显示出抑制控制受损. 这种缺陷源于前带带皮层 (OCD) 和右带岛 (EDs) 中明显的脑活动模式.

科学领域:

神经科学是一个神经科学.
精神病学是一个精神病学.
认知心理学认知心理学

背景情况:

强迫症 (OCD) 和饮食障碍 (ED) 具有共同的临床特征和受损的抑制控制.
抑制性控制缺陷是强迫症和ED之间潜在的共同联系.

研究的目的:

为了确定抑制控制是否是强迫症和ED之间共享的行为表型.
探索强迫症和ED中抑制控制缺陷的共同和独特的神经基础.

主要方法:

功能磁共振成像 (fMRI) 研究的定量元分析.
利用基于种子的d绘图 (SDM) 在抑制控制任务期间分析大脑功能.
包括16个强迫症fMRI研究和10个EDsfMRI研究.

主要成果:

与对照组和ED患者相比,患有强迫症的患者在前带带皮层表现出低活化.
与对照组和强迫症患者相比,患有ED的患者表现出右侧胰岛的低活性.
研究结果表明,强迫症和ED中抑制性控制缺陷的独特神经特征.

结论:

强迫症和ED都与抑制控制受损有关.
这些缺陷可能来自于特定大脑区域的神经激活的不同异常模式.
突出了强迫症和ED之间的潜在神经生物学区别.

关键词:

饮食障碍饮食障碍饮食障碍抑制性控制是一种抑制性控制.强迫症是一种强迫症.功能性磁共振成像功能性磁共振成像这是一个元分析.

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