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印纸产品中微量元素的存在:通过皮肤暴露进行非致癌风险评估
Joseph A Adeyemi1, Jonas C Cruz2, Tolulope V Ayo-Awe3
1Department of Clinical Analyses, Toxicology and Food Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Avenida do Café s/no, CEP 14040-903, Ribeirão Preto, São Paulo, Brazil; Department of Biology, School of Life Sciences, Federal University of Technology, P.M.B. 704, Akure, Ondo State, Nigeria.
Environmental research
|August 28, 2023
概括
这项研究发现,报纸和杂志等印刷纸张产品中微量元素的含量很低. 通过皮肤接触这些元素对人类健康没有重大风险.
科学领域:
- 环境科学 环境科学
- 毒理学 毒理学 毒理学
- 消费者产品安全 产品安全
背景情况:
- 对于印刷纸制品的皮肤暴露风险评估往往忽略了微量元素.
- 微量元素是已知的印刷油墨和调色剂的组成部分,但它们在纸制品中的含量尚未得到充分研究.
- 以前的研究主要集中在有机污染物,如双A (BPA).
研究的目的:
- 确定五种常见类型的印刷纸制品中各种微量元素的度.
- 通过皮肤暴露来估计这些元素的平均每日摄入量 (ADI).
- 评估与纸制品中微量元素的皮肤接触相关的潜在健康风险.
主要方法:
- 在公告,杂志,节目小册子,传单和报纸中分析微量元素度.
- 基于皮肤暴露的估计平均每日摄入量 (ADI) 的计算.
- 估计的ADI与已确定的皮肤参考剂量 (RfD) 的比较,用于毒理风险评估.
主要成果:
- 大多数微量元素 (除) 的高检测频率;没有检测到银 (Ag).
- 纸制品中的微量元素含量通常很低,与其他可能与皮肤接触的消费品相比.
- 所有分析元素的估计ADI显著低于它们各自的皮肤参考剂量 (RfDs).
结论:
- 从印刷纸制品中获得微量元素的皮肤暴露是最小的.
- 检测到的水平不会对人类造成重大非致癌健康风险.
- 这项研究为消费者产品关于微量元素暴露的风险评估提供了有价值的数据.
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