用光学连贯断层扫描测量视网膜厚度的评估在患有泛性焦虑症的患者中
Gulce Gokgoz Ozisik1, Seda Kiraz2
1Department of Ophthalmology, Faculty of Medicine, Hitit University, Corum, Turkey.
Photodiagnosis and photodynamic therapy
|August 28, 2023
概括
与健康对照人群相比,新诊断的泛性焦虑症患者在斑点,状细胞层和内状层的视网膜变薄. 这项研究突出了焦虑障碍潜在的眼部生物标志物.
科学领域:
- 眼科医生 眼科 眼科
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
背景情况:
- 泛性焦虑障碍 (GAD) 是一种普遍存在的心理健康状况.
- 眼睛结构,如视网膜,可能会受到系统性疾病的影响.
- 研究GAD的眼部变化可能会揭示新的生物标志物.
研究的目的:
- 为了比较视网膜神经纤维层 (RNFL) 厚度,斑点厚度,状细胞层 (GCL) 厚度和内状层 (IPL) 厚度,使用光学连贯断层 (OCT) 进行光学连贯断层扫描.
- 为了评估这些眼睛参数在新诊断的,无药物GAD患者与健康对照对比.
主要方法:
- 包括40名无药物GAD患者和43名健康对照.
- 通过OCT测量了RNFL,黄斑,GCL和IPL厚度.
- 管理的结构化临床访谈和国家特征焦虑度量表.
主要成果:
- 两组之间RNFL厚度没有显著差异.
- 在多个象限的GAD患者中观察到显著的黄斑稀释.
- 与对照组相比,在GAD患者的GCL和IPL中发现了统计学上显著的稀释.
结论:
- 这是第一个报告在新诊断的,无药物GAD患者中黄斑,GCL和IPL变薄的研究.
- 这些发现表明与GAD相关的潜在的眼睛结构变化.
- 需要进一步的研究来探索GAD中这些视网膜发现的临床含义.
相关概念视频
01:30Generalized Anxiety Disorder
165
Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
165
01:18Anxiety: Overview
300
Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
300
01:25Glaucoma: Overview
619
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
619