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高风险早产婴儿的呼吸系统管理和结果与人口结果仪表板的发展
Tng Chang Kwok1, Caroline Poulter2, Saleh Algarni3,4
1Centre for Perinatal Research, School of Medicine, University of Nottingham, Nottingham, UK.
Thorax
|August 28, 2023
概括
更多的早产婴儿存活下来,但有更糟糕的呼吸系统结果,包括严重的支气管肺功能障碍 (BPD). 这一趋势需要增加这些幸存者的慢性呼吸道疾病的医疗保健资源.
科学领域:
- 新生儿医学 新生儿医学
- 儿科肺病学 儿科肺病学
- 公共卫生 公共卫生
背景情况:
- 支气管肺功能障碍症 (BPD) 是早产婴儿长期呼吸和神经发育问题的重要原因.
- 缺乏关于呼吸系统管理和结果的最新人口层面数据,特别是严重的BPD.
研究的目的:
- 分析呼吸管理的时间趋势和早产婴儿 (<32周妊娠年龄) 的结果.
- 开发一个针对新生儿结局发生率的个性化仪表板.
主要方法:
- 利用国家新生儿研究数据库对英格兰和威尔士 (2010-2020) 83,463名早产婴儿进行了研究.
- 检查了呼吸支的变化,BPD率,出院后的支和死亡率.
- 开发了一个人口仪表板来可视化结果.
主要成果:
- 产前皮质类固醇的使用增加;新生儿表面活性剂的使用减少;产后皮质类固醇的使用增加 (德克萨米他,水皮,布德索尼德).
- 死亡率下降,但BPD,严重BPD和复合BPD/死亡结果增加.
- 出院后的呼吸支增加,婴儿需要在出院时提供压力支的数量显著增加.
结论:
- 早产婴儿的存活率正在增加,但往往有较差的呼吸道结果,特别是严重的BPD.
- 这些幸存者很可能会患上慢性呼吸道疾病,增加未来的医疗需求.
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