[血清液细胞病理学:国际系统:血清液的辅助研究和腹洗的特殊考虑]
Céline Basset1, Laetitia Collin2, Philippe Vielh3
1Département d'anatomie et de cytologie pathologiques, institut universitaire du cancer Toulouse oncopôle, 1, avenue Irène Joliot Curie, 31059 Toulouse cedex, France.
Annales de pathologie
|August 28, 2023
概括
现在,血清液细胞病理学国际系统已经整合了用于癌症诊断的分子标记物. 这些预后和预后标记在血清液和腹洗的细胞学样本上是可行的.
科学领域:
- 细胞病理学 细胞病理学
- 分子瘤学分子瘤学
- 癌症的诊断 癌症的诊断
背景情况:
- 血清液细胞病理学国际系统旨在标准化诊断术语.
- 分子变异发现的进步需要将它们整合到细胞学分析中.
- 血清性输液和腹洗是晚期癌症分期的关键样本类型.
研究的目的:
- 描述从血清液的细胞学样本上的分子标记物的指示和可行性.
- 报告常规癌症标的免疫细胞化学,FISH和核酸测试.
- 详细说明该分类对腹腔洗用于瘤分期的应用.
主要方法:
- 审查用于标记物识别的免疫细胞化学技术.
- 光在现场混合 (FISH) 的评估,用于目标检测.
- 对细胞学样本的DNA和RNA测试方法的评估.
- 对细胞采集的腹膜洗程序的分析.
主要成果:
- 大多数关键的分子标记物可以在输出液体上可靠地测试.
- 分子标记测试是可行的细胞学样本从血清液.
- 腹洗可以进行细胞学分析,有助于瘤分期和检测隐藏的恶性细胞.
结论:
- 更新的血清性输液液国际系统包含了分子病理学.
- 血清性输液的细胞学样本适用于预后和预后标志物测试.
- 腹膜洗为妇科和非妇科瘤提供了有价值的诊断信息.
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