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中国草药治疗伊利诺特干诱导的腹:一个系统的审查和元分析
XiaoLi Lin1, Yu Fang1, Yuan Cheng1
1Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China.
概括
中国草药 (CHD) 能够有效地预防伊利诺特干诱导的腹 (IID),这是结直肠癌治疗的常见副作用. 这种补充疗法显示出显著的保护作用,特别是在严重的腹中,副作用最小.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 氨酸是一种一线结直肠癌疗法,具有显著的毒性,特别是腹 (IID).
- 现有的IID治疗方法往往不令人满意.
- 中国草药 (CHD) 作为IID的补充和替代疗法正在探索中.
研究的目的:
- 系统地审查和元分析随机对照试验 (RCT).
- 评估心脏病对伊利诺特干诱导腹 (IID) 的预防作用.
主要方法:
- 系统搜索七个数据库的RCT在CHD上用于IID (1980-2022).
- 进行了偏差风险 (ROB 2.0) 和GRADE评估.
- 使用RevMan 5.3的元分析,包括子组分析和风险比率 (RR) 和95%置信区间 (CI) 的计算.
主要成果:
- 14个RCT (1056名参与者) 显示CHD降低了IID发病率 (RR=0.55).
- 与西方医学 (WM) 结合的CHD比单独的WM更有效 (RR=0.44),特别是在严重的腹 (RR=0.41).
- 班夏西 (Banxia Xie Xin) 蒸显示出高效率 (RR=0.18);黄 (Huangqin) 蒸得到了广泛的研究 (n=5,RR=0.56). 没有发现任何显著的不良反应.
结论:
- 冠状动脉病显示出对IID的预防作用.
- 冠心病可以用作补充疗法,具有良好的安全性.
- 建议进一步进行大规模,高质量,随机,双盲试验,以获得可靠的临床指导.
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