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Plk1通过准自/溶酶体轴来促进脏管间纤维化

Yang Du1,2,3, Yaqiong Shang1,2, Yun Qian1,2

  • 1Department of Nephrology, Children's Hospital of Nanjing Medical University, Guangzhou Road #72, Gulou District, 210008, Nanjing, China.

Cell death & disease
|August 28, 2023
PubMed
概括

波罗样酶1 (Plk1) 通过破坏自和溶酶体功能来驱动纤维化. 抑制Plk1可以通过减少纤维化和保护功能来治疗慢性病 (CKD).

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