糖尿病患者中胃衰竭的患病率:系统性审查和元分析
Lianxin Li1, Luyao Wang1, Ruolan Long1
1Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Scientific reports
|August 28, 2023
概括
糖尿病患者中糖尿病性胃衰竭 (DGP) 的综合患病率为9.3%,但研究结果显示高灵敏度和低强度. 亚组分析表明,患病率因性别,糖尿病类型,年龄和研究方法而异.
科学领域:
- 胃肠病学 胃肠病学
- 内分泌学 在内分泌学.
- 代谢疾病 代谢疾病
背景情况:
- 糖尿病性胃衰竭 (DGP) 是糖尿病 (DM) 的常见并发症.
- 了解DGP的患病率和相关因素对于患者管理至关重要.
- 之前的研究报告了不同的患病率,需要进行全面的元分析.
研究的目的:
- 为了确定糖尿病患者糖尿病性胃衰竭 (DGP) 的整体综合流行率.
- 通过子组分析,调查影响DGP流行的潜在因素.
主要方法:
- 进行了一项元分析,将多项研究的流行数据汇集在一起.
- 进行了敏感性分析,以评估研究结果的可靠性.
- 亚组分析检查了性别,年龄,糖尿病类型和研究方法对患病率的影响.
主要成果:
- 据估计,DGP的整体综合流行率为9.3%.
- 患病率在女性 (4.6%) 比男性 (3.4%) 和2型糖尿病 (12.5%) 和1型糖尿病 (8.3%) 相比更高.
- 在60岁以上的患者中,DGP的患病率较低 (5.5%),而在60岁以下的患者中 (15.8%),在分析中发现了显著的异质性.
结论:
- 糖尿病胃衰竭的患病率受性别,糖尿病类型,年龄和研究方法的影响.
- 尽管综合流行率为9.3%,但结果显示出高灵敏度和低稳定性,表明了显著的偏差因素.
- 需要进一步的研究来证实这些发现,并探索潜在的机制.
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