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基于MRI的脊椎骨质量评分:与年龄和可再生性的关系

Daniel Liu¹, Aamir Kadri², Diego Hernando³

¹Department of Orthopedics and Rehabilitation, School of Medicine and Public Health, University of Wisconsin, 600 Highland Ave, Madison, WI, 53792-3252, USA. dliu83@wisc.edu.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

|August 28, 2023

概括

脊椎骨质量 (VBQ) 评分与年龄相关,并且可以在连续的MRI扫描中重现. 标准化MRI技术因素对于准确的骨矿物质密度估计至关重要.

科学领域:

放射学放射学是一门学科.
整形外科整形外科整形外科
骨健康骨健康骨健康

背景情况:

脊椎骨质量 (VBQ) 评分是骨矿物质密度 (BMD) 的机会性测量,用于脊柱手术中的常规手术前MRI.
众所周知,VBQ得分与年龄相关,并在串行扫描中显示可重现性.
然而,像MRI机器和协议这样的外部因素可能会影响VBQ得分,需要标准化.

研究的目的:

为了确定VBQ得分是否随着患者年龄的增加而增加.
评估VBQ得分在3个月间进行的连续MRI研究中的一致性.

主要方法:

追溯分析136名患者 (20-69岁) 连续T1加权腰部MRI在3个月内.
使用信号强度比率 (脊椎与CSF) 计算的VBQ (L1-4) 和VBQ (L1) 评分.
对于年龄相关性的回归分析和可复制性的变化系数 (CV).

主要成果:

在控制MRI放松/回声时间时,VBQ ((L1-4) 评分与年龄呈正相关.
在连续MRI中VBQ(L1-4) 评分的出色可重现性 (CV = 0.169).
在VBQ (L1) 和VBQ (L1-4) 分数之间达成高度一致 (ICC > 0.9).

结论:

年龄和MRI技术因素影响VBQ得分,需要考虑BMD估计.
VBQ评分与年龄的正相关性和优异的可重现性支持其用于估计骨质量.
VBQ (L1) 评分作为VBQ (L1-4) 的可靠替代品来评估骨质.

关键词:

优化骨健康优化骨健康磁共振成像技术磁共振成像技术机会性查是一种机会性查.整形外科手术整形外科手术骨质疏松症是一种骨质疏松症.脊柱外科手术脊柱外科手术

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