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Updated: Jul 17, 2025

Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C
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scNanoHi-C:一种单细胞长读结合体测序方法,用于揭示单细胞内的高阶染色体结构

Wen Li1,2,3,4, Jiansen Lu1,3,4, Ping Lu1,3

  • 1School of Life Sciences, Biomedical Pioneering Innovative Center, Peking University, Beijing, China.

Nature methods
|August 28, 2023
PubMed
概括

我们开发了scNanoHi-C,这是一种使用纳米孔测序来绘制单细胞中高阶3D基因组结构的新方法. 这种技术揭示了复杂的染色质相互作用,并有助于基因组变异检测.

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