2005-2017年中国白血病的流行病学特征:日志线性回归和年龄周期队列分析
Kangqian Lin1, Huaimiao Jia2, Miao Cao1
1Department of Preventive Medicine, School of Medicine, Shihezi University, Shihezi, Xinjiang, China.
BMC public health
|August 28, 2023
概括
中国的白血病发病率正在上升,男性和城市地区的发病率更高. 虽然死亡率最初上升,但在2012年左右开始下降,特别是在年轻年龄组. 这凸显了持续预防白血病的必要性.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 癌症研究 癌症研究
背景情况:
- 白血病在全球范围内构成重大公共卫生威胁.
- 关于中国白血病发病率,死亡率和疾病负担的研究有限.
- 了解这些趋势对于有效的白血病控制策略至关重要.
研究的目的:
- 分析2005年至2017年期间中国白血病发病率和死亡率的趋势.
- 为了研究年龄-时期-队列对白血病率的影响.
- 为白血病预防和控制提供数据驱动的见解.
主要方法:
- 利用了来自中国癌症登记处年度报告 (2005-2017年) 的白血病发病率和死亡率数据.
- 员工加入点回归来评估时间趋势 (AAPC和APC).
- 构建了一个年龄-时期-队列模型来分析人口统计的影响.
主要成果:
- 年龄标准化白血病发病率每年增加1.9% (AAPC).
- 死亡率上升到2012年,然后下降,男性的发病率和死亡率更高.
- 白血病的风险随着年龄的增长而增加,0-4岁的儿童尤其容易受到影响. 农村发病率虽然较低,但增长速度更快.
结论:
- 中国的白血病发病率显示出持续的上升趋势.
- 死亡率在2012年左右达到峰值,自那以后一直在下降.
- 根据性别,地区和年龄的显著差异强调了有针对性的公共卫生干预措施的必要性.
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