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Updated: Jul 17, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
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Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

Published on: January 26, 2024

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3DDPDs:描述蛋白质动态,用于蛋白质化学测量生物活性预测. 对于 (突变的) G 蛋白结合受体的一个例子

Marina Gorostiola González1,2, Remco L van den Broek1, Thomas G M Braun1

  • 1Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.

Journal of cheminformatics
|August 28, 2023
PubMed
概括

新的3D动态蛋白质描述器 (3DDPDs) 捕获蛋白质运动,以改善药物发现模型. 这些动态特征增强了生物活性预测,在关键任务中表现优于传统的静态方法.

关键词:
3DDPDD 3DDPD是什么意思在GPCR中,GPCR是指GPCR.分子动力学分子动力学蛋白质描述器是一种蛋白质描述器.蛋白质化学测量学 蛋白质化学测量

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