结肠炎相关结肠直肠癌与性结肠炎的临床特征和手术选择
Ryuichi Kuwahara1, Hiroki Ikeuchi2, Kurando Kusunoki2
1Department of Gastroenterological Surgery, Division of Inflammatory Bowel Disease Surgery, Hyogo Medical University, Nishinomiya, Japan. ri-kuwahara@hyo-med.ac.jp.
由于癌症/发育不良而接受手术的性结肠炎患者往往比耐火性疾病患者有更轻微的疾病和更好的营养. 这突显了手术干预患者个人资料的关键差异.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 炎症性肠道疾病研究研究
背景情况:
- 性结肠炎 (UC) 管理包括针对耐火性疾病或癌症/发育不良的手术.
- 了解这些患者群体之间的临床差异对于手术规划至关重要.
研究的目的:
- 为了比较UC患者的临床特征进行癌症/发育不良手术与耐火性疾病.
- 讨论手术前的准备,以获得成功的手工皮皮囊-门解剖 (IPAA).
主要方法:
- 在医科大学对443例UC手术病例 (2014-2021) 的回顾性分析.
- 188名癌症/发育不良患者与255名耐火患者的比较.
主要成果:
- 癌症/发育不良的UC手术的比例正在增加 (~40%).
- 癌症/发育不良症患者的疾病持续时间较长 (186个月与48个月),UC严重程度较轻 (p<0.01),营养状况更好 (体重,BMI,白蛋白,PNI) (p<0.01).
- 在癌症/发育不良组 (p<0.01) 观察到更高的肥胖程度.
结论:
- 与耐火性疾病患者相比,UC癌症/发育不良患者的炎症和营养状况较好.
- 较长的疾病持续时间是癌症/发育不良组的特征.
- 这些发现为性结肠炎手术管理的术前策略提供了信息.
更多相关视频
00:08Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
Published on: August 24, 2019
08:26Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
相关概念视频
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Drugs for Treatment of Ulcerative Colitis in IBD
