短期腹腔玉米粉输液对腹腔发酵和血液测量的影响
S K Cronin1, A M Barnard1, S J Dietz1
1Department of Animal and Food Sciences, University of Delaware, Newark, DE 19716.
Journal of dairy science
|August 29, 2023
概括
增加牛的肠粉发酵并没有引发炎症反应. 面玉米粉注入导致便测量有轻微变化,但没有诱导后肠酸或影响急性阶段蛋白质.
科学领域:
- 动物的营养和生理学
- 胃肠道微生物学和免疫学
- 乳牛的健康和新陈代谢.
背景情况:
- 亚急性粉酸性粉症 (SARA) 可能导致系统性影响,可能与肠粉发酵有关.
- 了解后肠粉发酵对奶牛健康的影响对于管理代谢障碍至关重要.
研究的目的:
- 研究腹腔玉米粉输液对便发酵标记物,血急性相蛋白和哺乳乳奶牛白血细胞群的影响.
- 为了确定增加后肠粉发酵是否会诱导全身炎症反应.
主要方法:
- 在每21天的最后7天内,在6只经过小吃的奶牛被分配到3x3拉丁方形设计中,在每21天的最后7天内,给它们注入腹腔玉米粉输液 (0,1,或3g/kg体重).
- 便样本分析了pH值,挥发性脂肪酸 (VFA),乳酸和脂聚糖 (LPS).
- 采集血液样本以测量血急性阶段蛋白质 (黑球蛋白,血清粉样蛋白A) 和白细胞种群,包括γδ T 细胞.
主要成果:
- 面玉米粉输液线性降低了便的pH值,增加了便的VFA和LPS,但这些变化很小,并没有表明后肠酸性.
- 没有观察到治疗对明显的全道粉消化能力,便粉含量,血清急性阶段蛋白质或大多数循环白细胞的显著影响.
- 在增加腹腔玉米粉时,观察到循环的 γδ T 细胞比例线性下降的趋势.
结论:
- 与假设相反,在测试水平上增加后肠粉发酵并没有引起哺乳乳奶牛的显著炎症反应.
- 便参数的适度变化表明,奶牛的胃肠道可以耐受后肠粉发酵的适度增加,而不会诱导酸或全身炎症.
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