精确癌症医学:概念,现行实践和未来发展
Anders Edsjö1,2,3, Louise Holmquist1,3, Birgit Geoerger4,5
1Department of Clinical Genetics, Pathology and Molecular Diagnostics, Office for Medical Services, Region Skåne, Lund, Sweden.
Journal of internal medicine
|August 29, 2023
概括
精确癌症医学的进步依赖于可扩展的分子诊断和适应性测试,以实现个性化瘤学. 未来的进展取决于智能临床试验和协作网络,以改善患者的治疗结果.
科学领域:
- 在瘤学瘤学.
- 基因组学就是基因组学.
- 翻译医学是一种翻译医学.
背景情况:
- 精准癌症医学在过去二十年中取得了重大进展.
- 未来的发展需要将复杂的分子数据整合到临床实践中.
研究的目的:
- 审查诊断工具,临床研究和合作努力,以推进精确的癌症医学.
- 突出可扩展的诊断和适应性分析的重要性.
主要方法:
- 审查当前的诊断技术,包括基于组织和液体的测试.
- 分析创新的临床试验设计和现实世界的证据的作用.
- 审查监管和卫生技术评估协调.
主要成果:
- 可扩展的分子诊断和适应性分析对于将复杂数据转化为可操作的临床信息至关重要.
- 智能临床试验和现实世界的证据对于扩大治疗选择至关重要.
- 多中心网络是实施精密瘤学和改善患者护理的关键.
结论:
- 精准癌症医学是一个多学科的努力,需要社会参与.
- 集成先进的诊断,适应性策略和协作研究对于未来的进步至关重要.
- 与监管机构和国际网络的协调对于实现精密瘤学的全部潜力至关重要.
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