多焦点视觉唤起的潜力,用于评估开放角眼
Mostafa EmadEldeen Hussien Mohamed Afify1, Randa Hesham Ali Abdelgawad1, Momen Mahmoud Hamdi1
1Ophthalmology Department, Ain Shams University Hospitals, Cairo, Egypt.
Medical hypothesis, discovery & innovation ophthalmology journal
|August 29, 2023
概括
多焦视觉唤起潜力 (mfVEP) 在评估初级开角青光眼 (POAG) 方面表现有前途. 这种客观工具与POAG患者的视野和光学连贯性断层扫描 (OCT) 测量良好相关.
科学领域:
- 眼科医生 眼科 眼科
- 神经科学是一个神经科学.
- 医疗成像医学成像
背景情况:
- 主要开角青光眼 (POAG) 是不可逆转失明的主要原因.
- 准确评估视野 (VF) 和视网膜神经纤维层 (RNFL) 厚度对于POAG管理至关重要.
- 需要客观的电生理学工具来补充现有的诊断方法.
研究的目的:
- 将多焦视觉唤起潜力 (mfVEP) 发现与静态自动周边测量 (SAP) 和光谱域光学连贯断层扫描 (SD-OCT) 在眼睛中与POAG相关联.
- 评估mfVEP作为POAG视觉功能客观测量的潜力.
主要方法:
- 对40名POAG患者的40只眼睛进行横截面研究.
- 综合眼科评估,包括轴长度测量.
- 使用SAP,SD-OCT和mfVEP进行评估.
主要成果:
- mfVEP上环信号噪声比 (SNR) 与视觉敏度有负相关性,与较高的视频频率和较低的RNFL厚度有正相关性.
- mfVEP下环SNR与视力敏度有负相关,与较低的视力敏度和较高的RNFL厚度有正相关.
- 这些相关性表明,mfVEP反映了POAG中的玻璃眼损伤.
结论:
- mfVEP是一种有前途的客观工具,用于评估POAG患者的视野.
- mfVEP的发现与VF和OCT RNFL厚度正相关.
- 需要进一步的纵向研究,采用更大的样本大小来证实这些初步发现.
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