Bsep/Abcb11淘汰赛通过减少寄生虫生育能力来改善Schistosoma mansoni肝脏病理

Tomáš Macháček1,2, Claudia D Fuchs3, Franziska Winkelmann1

  • 1Division of Tropical Medicine and Infectious Diseases, Center of Internal Medicine II, Rostock University Medical Center, Rostock, Germany.

概括

在 Schistosoma mansoni 感染后,缺乏胆汁载体 Bsep 的小鼠表现出肝炎和纤维化减少. 这表明胆酸的变化可能会防止寄生虫诱导的肝损伤.

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