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Updated: Jul 17, 2025

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基于结构的设计,以提高阿尔多-基因还原酶KdAKRR的催化性能

Chen Dai1,2,3, Hai-Xing Cao1,2,3, Jia-Xin Tian1,2,3

  • 1Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, People's Republic of China.

Biotechnology and bioengineering
|August 29, 2023
PubMed
概括

工程化生物催化剂称为阿尔多-基因还原酶 (AKRs) 显示增强的活性和稳定性,用于合成性酒精. 一种经过修改的KdAKR酶显著提高了催化效率和立体选择性,有助于制药生产.

关键词:
阿尔多-凯托减少酶催化活动的催化活动.立体选择性的立体选择性.基于结构的设计设计.热稳定性 热稳定性

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