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Oral Health Assessment by Lay Personnel for Older Adults
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老年人甲状腺功能低下症:叙述性审查
Vincenzo Fiore1, Alessandra Barucca1, S Barraco1
1UOSD Diabetologia – Endocrinologia, ASL RM5, Rome, Italy
Endocrine, metabolic & immune disorders drug targets
|August 29, 2023
概括
甲状腺功能低下症在老年人中很常见,通常是由药物或自身免疫性疾病引起的. 对老年患者的治疗决策需要仔细评估风险和益处,在明显的病例中优先选择勒沃西.
科学领域:
- 老年医学 老年医学
- 内分泌学 在内分泌学.
- 甲状腺学 甲状腺学
背景情况:
- 甲状腺功能低下症的患病率随着年龄的增长而上升,在75岁以上的个人中成为一种常见的并发症.
- 老年人的关键原因包括阳性因素,哈西莫托甲状腺炎和药物.
- 与年龄相关的生理变化影响甲状腺功能,需要仔细解释甲状腺刺激激素 (TSH) 水平.
研究的目的:
- 审查老年人甲状腺功能低下症的临床特征.
- 评估激素替代疗法对老年人生存的影响.
- 引导老年人群中甲状腺功能低下症的诊断和治疗策略.
主要方法:
- 关于老年人甲状腺功能低下症现有文献的叙述性综述.
- 对诊断工作的分析,以区分真正的甲状腺功能低下症及其原因.
- 评估治疗考虑因素,包括levothyroxine治疗和TSH目标.
主要成果:
- 仅仅血清TSH升高并不能证实甲状腺功能低下症;诊断工作至关重要.
- 利沃甲状腺素治疗适用于明显的甲状腺功能低下症.
- 亚临床甲状腺功能低下症的管理需要风险效益分析,特别是在75岁以下的患者中.
结论:
- 个性化管理对于患有甲状腺功能低下症的老年患者至关重要.
- 优选的是提高吸收和遵守的levothyroxine配方.
- 通常设置在3mIU/ml以上的TSH目标可能是适当的,考虑到个体患者的因素.
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