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痴呆症自杀行为的决定因素:基于瑞典国家登记册的研究
Khedidja Hedna1,2,3, Robert Sigström1,2,4, Kristina Johnell5
1AgeCap Center, Department of Psychiatry and Neurochemistry, Gothenburg University, Gothenburg, Sweden.
International psychogeriatrics
|August 29, 2023
概括
患有痴呆症的老年人中自杀行为风险高于先前的自我伤害,抑郁和外国背景. 家庭护理可以降低这种风险.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 痴呆症影响着越来越多的老年人群,增加了对心理健康问题的脆弱性.
- 痴呆症老年人的自杀行为 (SB) 是一个重大问题,需要进一步调查.
- 在这个人口群体中,SB的预测因素尚未完全理解,需要有针对性的研究.
研究的目的:
- 确定75岁及以上被诊断患有痴呆症的个体中自杀行为 (SB) 的预测因素.
- 为了探索与SB相关的人口统计学,并发症和药物相关的因素,在这个人群中.
- 为预防老年痴呆症患者SB的公共卫生策略提供信息.
主要方法:
- 采用了基于国家注册的纵向研究设计.
- 分析了2007-2017年间发现的75岁以上痴呆症的59,042名瑞典居民的数据.
- 用精细和灰色回归模型来评估各种因素与SB结果之间的关联.
主要成果:
- 以前的自我伤害,严重的抑郁和出生在国外是增加SB风险的重要预测因素.
- 催眠药或焦虑缓解药的使用与较高的SB风险有关,而抗抑郁药并非如此.
- 较轻度的痴呆症,较高的脆弱性和接受家庭护理与SB风险有关,家庭护理显示有保护作用.
结论:
- 已经确定的SB风险因素,如抑郁症和先前的自我伤害,仍然是干预的关键目标.
- 新的风险因素,包括外国背景和特定药物使用,突出显示出需要量身定制的公共卫生方法.
- 家庭护理可能在痴呆症患者中提供对SB的保护性益处,这需要进一步的研究和探索.
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