在COVID-19世界流行病期间的癌症管理
Navid Sobhani1, Giuseppina Mondani2, Giandomenico Roviello3
1Department of Medicine, Section of Epidemiology and Population Sciences, Baylor College of Medicine, Houston, TX, 77030, USA. NSobhani@mdanderson.org.
Cancer immunology, immunotherapy : CII
|August 29, 2023
概括
在癌症患者中管理COVID-19至关重要,因为他们的易感性增加和严重后果的风险增加. 本综述概述了根据个体患者需求和癌症特征量身定制的基本管理策略.
科学领域:
- 传染性疾病 传染性疾病
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 由SARS-CoV-2引起的COVID-19大流行,对全球健康构成了重大挑战.
- 由于免疫抑制性癌症治疗,癌症患者对COVID-19具有独特的脆弱性,导致潜在的预后较差.
- 多器官衰竭,可能与广泛的ACE2受体表达有关,导致COVID-19的高死亡率.
研究的目的:
- 审查和综合有关癌症患者管理COVID-19的当前知识.
- 为治疗策略提供指导,考虑癌症特异性因素和患者分层.
- 为了强调在COVID-19大流行期间为这个弱势群体提供个性化护理的重要性.
主要方法:
- 文献综述侧重于癌症和COVID-19管理的交叉点.
- 分析影响癌症患者COVID-19结果的因素,包括癌症类型,阶段和治疗方法.
- 对患者分层和量身定制的治疗方法的综合建议.
主要成果:
- 癌症患者面临严重COVID-19和相关并发症的风险增加.
- 对于患有COVID-19的癌症患者的治疗决定需要仔细的个案评估.
- 基于受影响的器官和瘤阶段的分层是有效管理的必要条件.
结论:
- 在癌症患者中有效管理COVID-19需要个性化的方法.
- 了解癌症,癌症治疗和SARS-CoV-2感染之间的相互作用至关重要.
- 本综述为优化护理和改善COVID-19大流行期间癌症患者的治疗结果提供了一个框架.
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